Analysis of genome-wide association data by large-scale Bayesian logistic regression
نویسندگان
چکیده
منابع مشابه
Analysis of genome-wide association data by large-scale Bayesian logistic regression
Single-locus analysis is often used to analyze genome-wide association (GWA) data, but such analysis is subject to severe multiple comparisons adjustment. Multivariate logistic regression is proposed to fit a multi-locus model for case-control data. However, when the sample size is much smaller than the number of single-nucleotide polymorphisms (SNPs) or when correlation among SNPs is high, tra...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2009
ISSN: 1753-6561
DOI: 10.1186/1753-6561-3-s7-s16